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KMID : 1144520180300030179
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Knee Surgery & Related Research
2018 Volume.30 No. 3 p.179 ~ p.186
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Infrapatellar Fat Pad-Derived Stem Cell-Based Regenerative Strategies in Orthopedic Surgery
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Huri Pinar Yilgor
Hamsici Seren
Ergene Emre
Huri Gazi
Doral Mahmut Nedim
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Abstract
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Infrapatellar fat pad is a densely vascularized and innervated extrasynovial tissue that fills the anterior knee compartment. It plays a role in knee biomechanics as well as constitutes a source of stem cells for regeneration after knee injury. Infrapatellar fat pad-derived stem cells (IPFP-ASCs) possess enhanced and age-independent differentiation capacity as compared to other stem cells, which makes them a very promising candidate in stem cell-based regenerative therapy. The aims of this review are to outline the latest advances and potential trends in using IPFP-ASCs and to emphasize the advantages over other sources of stem cells for applications in orthopedic surgery.
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KEYWORD
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Knee, Fat pad, Stem cell
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